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Clean is the opposite of dirty. Clear means transparent or unclouded: clear water, a clear sky.
Little means not much and emphasises the smallness of the amount. It's distinguished from a little which means at least some.
Few means not many and emphasises the smallness of the number, it is distinguished from a few, which means at least some.
To be ill means to be in bad health. To be sick means to vomit. We sometimes use sick idiomatically to mean feeling ill. The smell made me sick.
We can also use sick before certain nouns: The sick room, a sick note, sick leave. We use the plural noun the sick to mean ill people: Angela worked with the sick on the streets of Birmingham.
We usually use some for affirmative phrases: She's got some chicken, and any in negative and interrogative phrases: Ian hasn't bought any food today. Have you bought any food? We sometimes use some in questions: Would you like some soup?